Hypoxia Activates FGF-23-ERK/MAPK Signaling Pathway in Ischemia-Reperfusion-Induced Acute Kidney Injury
FGF-23 is a key molecule in AKI, and hypoxia plays a crucial role in AKI by inducing cell apoptosis; however, its role is regulated by FGF-23. FGF-23 affects oxidative stress and the inflammatory response of kidney tissues by activating the ERK/mitogen-activated protein kinase (MAPK) signaling pathway.
Authors
- Weihua Liu (ORCID: https://orcid.org/0000-0002-8527-9973)
- Fu‐Yuan Hong (ORCID: https://orcid.org/0000-0001-5627-9088)
- Yiping Dai
- Miao Lin (ORCID: https://orcid.org/0009-0004-2634-3690)
Institutions
- Fujian Medical University (CN)
- Fujian Provincial Hospital (CN)
Publication Details
- Journal
- Kidney & Blood Pressure Research
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1159/000541388
- Citations
- 3
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.72