Systemic Innate Immune System Restoration as a Therapeutic Approach for Neurodegenerative Disease: Effects of NP001 on Amyotrophic Lateral Sclerosis (ALS) Progression
The observed longer survival in ALS patients with the greatest inflammation-associated muscle loss provides further evidence that ALS is a disease of ongoing innate immune dysfunction and that NP001 is a disease-modifying drug with sustained clinical activity.
Authors
- Ari Azhir
- B. D. Forrest (ORCID: https://orcid.org/0009-0003-3348-8604)
- Paige M. Bracci (ORCID: https://orcid.org/0000-0001-9338-9307)
- Michael S. McGrath (ORCID: https://orcid.org/0000-0002-7232-2602)
- Rongzhen Zhang (ORCID: https://orcid.org/0000-0002-5745-1190)
Institutions
- Hudson Institute (US)
- University of California, San Francisco (US)
Publication Details
- Journal
- Biomedicines
- Published
- 2024-10-16
- DOI
- https://doi.org/10.3390/biomedicines12102362
- Citations
- 2
- Primary Topic
- Amyotrophic Lateral Sclerosis Research
- Type
- article
- Field-Weighted Citation Impact
- 0.74