AR expression-independent XRCC3 mediates DNA damage-induced p53/Bax signaling pathway activation against prostate cancer
Silencing XRCC3 exerts anti-PCa effects by promoting DNA damage-induced p53/Bax signaling pathway activation in an AR expression-independent manner.
Authors
- Jing Ning (ORCID: https://orcid.org/0000-0002-5289-331X)
- Yi Cen (ORCID: https://orcid.org/0009-0003-9320-4634)
- Chong Sun (ORCID: https://orcid.org/0000-0001-9008-2158)
- Jinxian Pu (ORCID: https://orcid.org/0000-0002-0501-5178)
- Hailong Xie
- Haiyan Wang (ORCID: https://orcid.org/0009-0004-5716-8565)
- Guangbin Zhu (ORCID: https://orcid.org/0009-0000-6798-2107)
- Mingjiang Dan
- Shourui Feng
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Sun Yat-sen University (CN)
- Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- The Second Affiliated Hospital of Bengbu Medical College (CN)
- First Affiliated Hospital of Soochow University (CN)
- The Fourth Affiliated Hospital of Soochow University (Suzhou Dushu Lake Hospital)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1007/s00432-024-05989-8
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00