MiR-27a inhibits the growth and metastasis of multiple myeloma through regulating Th17/Treg balance
Our study revealed that miR-27a inhibited MM evolution by regulating the Th17/Treg balance. Inhibition of the PI3K/AKT/mTOR signaling pathway by miR-27a may play a potential mechanistic role.
Authors
- Mingfeng Xiao (ORCID: https://orcid.org/0000-0002-5990-2223)
- Hui Huang (ORCID: https://orcid.org/0000-0002-2279-8418)
- Kewei Zhao (ORCID: https://orcid.org/0000-0002-0500-5295)
- Shumin Xu
- Zhanjie Xu
- Weiguo Lu
Institutions
- Guangzhou University of Chinese Medicine (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1371/journal.pone.0311419
- Citations
- 5
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.27
Funders
- Guangdong Medical Research Foundation
- Traditional Chinese Medicine Bureau of Guangdong Province