[Mechanism of analgesic effect of electroacupuncture on rats with cervical spondylosis radiculopathy based on activation of astrocytes and HMGB1/TLR4/MyD88 signaling pathway].
EA can effectively alleviate pain in CSR rats, which is possibly by inhibiting astrocyte activation, HMGB1/TLR4/MyD88 signaling pathway, and reducing the release of related inflammatory cytokines, thus alleviating central sensitization in spinal segments.
Authors
- Cai-Yun Xie (ORCID: https://orcid.org/0000-0001-8317-8493)
- Pu Yang (ORCID: https://orcid.org/0000-0002-6231-4721)
- Hong Su (ORCID: https://orcid.org/0009-0001-7316-970X)
- Jing Li (ORCID: https://orcid.org/0000-0001-9392-6600)
- Sheng-Yong Su
- Yanjun Guo (ORCID: https://orcid.org/0000-0002-5927-778X)
Institutions
- Guangxi University of Chinese Medicine (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-10-14
- DOI
- https://doi.org/10.13702/j.1000-0607.20230789
- Citations
- 3
- Primary Topic
- Cervical and Thoracic Myelopathy
- Type
- article