Cofilin linked to GluN2B subunits of NMDA receptors is required for behavioral sensitization by changing the dendritic spines of neurons in the caudate and putamen after repeated nicotine exposure
These findings suggest that active cofilin alters the structure of spine heads from mushroom to thin spine/filopodia by potentiating actin turnover, contributing to behavioral sensitization after nicotine exposure.
Authors
- Eun Sang Choe (ORCID: https://orcid.org/0000-0001-5868-7747)
- Sumin Sohn (ORCID: https://orcid.org/0000-0002-9523-8235)
- Sunghyun Kim (ORCID: https://orcid.org/0000-0003-3227-894X)
Institutions
- Pusan National University (KR)
Publication Details
- Journal
- Behavioral and Brain Functions
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1186/s12993-024-00253-y
- Citations
- 1
- Primary Topic
- Neurotransmitter Receptor Influence on Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.27
Funders
- National Research Foundation
- National Research Foundation of Korea