The relationship between serum HDL-cholesterol, cardiovascular disease and mortality in community-based people with type 2 diabetes: the Fremantle Diabetes Study phase 2
There was a significant U-shaped relationship between serum HDL-cholesterol and both 3-point MACE and all-cause death in females with type 2 diabetes after adjustment for confounders. There was no such relationship for 3-point MACE in males but a low HDL-cholesterol was associated with all-cause mortality. These data have sex-specific implications for assessment of serum lipid profiles in the clinical management of type 2 diabetes.
Authors
- S. A. Paul Chubb (ORCID: https://orcid.org/0000-0002-6742-4110)
- Wendy A. Davis (ORCID: https://orcid.org/0000-0002-5709-8235)
- Timothy M. E. Davis (ORCID: https://orcid.org/0000-0003-0749-7411)
Institutions
- The University of Western Australia (AU)
- Fiona Stanley Hospital (AU)
- Fremantle Hospital (AU)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1186/s12933-024-02447-0
- Citations
- 4
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Medical Research Council
- National Health and Medical Research Council