[Effect of electroacupuncture at "Fenglong" (ST 40) on liver cholesterol metabolism in hyperlipidemia rats based on AMPK/mTOR pathway].
EA at "Fenglong" (ST 40) can attenuate hyperlipidemia in HPL rats. It may be achieved by regulating the AMPK/mTOR pathway, inhibiting the expression of cholesterol synthesis related molecules, SREBP-2 and HMGCR, and up-regulating the expression of cholesterol excretion molecules, ABCG5 and ABCG8, thereby reducing liver cholesterol accumulation and increasing cholesterol excretion.
Authors
- Xiaoli Pan (ORCID: https://orcid.org/0000-0002-5033-7272)
- Manqi Liu
- Jia‐Bao Liu (ORCID: https://orcid.org/0000-0002-9620-7692)
- Dan Li (ORCID: https://orcid.org/0000-0002-4812-5000)
- Hongxing Zhang (ORCID: https://orcid.org/0000-0002-7929-0324)
- Shuwen Jin (ORCID: https://orcid.org/0009-0006-5002-4192)
- Xi Zhang (ORCID: https://orcid.org/0009-0007-1790-5884)
Institutions
- Hubei University of Chinese Medicine (CN)
- Jianghan University (CN)
- China Association of Acupuncture-Moxibustion (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-10-12
- DOI
- https://doi.org/10.13703/j.0255-2930.20231011-k0002
- Citations
- 1
- Primary Topic
- Traditional Chinese Medicine Studies
- Type
- article