Diagnostic Accuracy of Ultrasound in Detecting Malignant Thyroid Nodules Keeping Histopathology as Gold Standard

Objective: To determine the diagnostic accuracy of ultrasound in the detecting malignant thyroid nodule keeping histopathology as a gold standard. Methodology: In the current study a total of 164 patients were included. A detail history, routine hospital investigations and physical examination for the included patients were performed. Patients were subjected to ultrasound in Radiology department where the ultrasound was done by the senior resident under the supervision of expert radiologist having more than 7 years of ex-perience. The nodules were reported according to ACR TI-RADS. Then the patients were referred to ENT department where the incisional biopsy were performed and the specimen was sent to hospital laboratory for the diagnosis of malignant thyroid nodule. All the histopathological examinations were done by expert histo-pathologist having more than 7 years of experience. Results: In this study total 164 patients were included and mean age was 34 years with SD ± 7.318. Male patients were 62(38%) while 102(62%) patients were female. Ultrasound had sensitivity 96.58%, specificity 83.33%, positive predictive value 76.65%, negative predictive value 97.72% and the diagnostic accuracy was 88.12%. Conclusion: Our study concludes that ultrasound had sensitivity 96.58%, specificity 83.33%, positive predictive value 76.65%, neg-ative predictive value 97.72% and the diagnostic accuracy was 88.12% in the detecting malignant thyroid nodule keeping histo-pathology as a gold standard.