Rationale for irradiation of persisting oligo‐skeletal metastases to improve survival of metastatic neuroblastoma patients with a poor response to chemotherapy: A retrospective study
Our study underlines that only a minority of patients had persistent skeletal mIBG-positive scans after HDC. Recurrence mainly occurred in disease sites present at diagnosis that cleared with chemotherapy. On-therapy control of the disease is the main challenge. These results highlight the complexity of conducting a randomized study exploring this strategy.
Authors
- Christelle Dufour (ORCID: https://orcid.org/0000-0001-5993-8077)
- Véronique Edeline (ORCID: https://orcid.org/0000-0002-2720-9803)
- Stéphanie Bolle (ORCID: https://orcid.org/0000-0003-1311-9214)
- Pablo Berlanga (ORCID: https://orcid.org/0000-0003-1110-7789)
- Laurențiu Agrigoroaie (ORCID: https://orcid.org/0000-0002-8831-9133)
- Claudia Pasqualini (ORCID: https://orcid.org/0000-0002-1113-2792)
- Lea Rossillon (ORCID: https://orcid.org/0000-0003-3936-5595)
Institutions
- Institut Gustave Roussy (FR)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1002/pbc.31350
- Citations
- 1
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.37