Chemotherapy-induced cognitive impairment and its long-term development in patients with breast cancer: results from the observational CICARO study
Our findings suggest that chemotherapy statistically significantly contributes to overall cognitive dysfunction in patients with breast cancer, which disappears after 2-3 years, indicating a recovery in both objectively measurable cognitive function and subjective quality of life. Future research should examine larger sample sizes and explore screening indicators, particularly pNfH.
Authors
- Adam Dordevic
- Nikola Bangemann
- Matthias Endres (ORCID: https://orcid.org/0000-0001-6520-3720)
- Christian Schinke (ORCID: https://orcid.org/0000-0003-0199-9672)
- Petra Huehnchen (ORCID: https://orcid.org/0000-0002-6825-7270)
- Jens‐Uwe Blohmer (ORCID: https://orcid.org/0000-0002-7969-250X)
- Bianca Materne
- Johannes Steffen Kern (ORCID: https://orcid.org/0000-0001-6372-8048)
- Klemens Ruprecht (ORCID: https://orcid.org/0000-0003-1962-6014)
- Josefine Finck
- Carolin Otto (ORCID: https://orcid.org/0000-0002-9768-5143)
- Wolfgang Boehmerle (ORCID: https://orcid.org/0000-0001-7195-3894)
- Jens Göpfert (ORCID: https://orcid.org/0000-0003-3525-3684)
- Anna Kerkmann (ORCID: https://orcid.org/0009-0005-6650-5831)
Institutions
- German Center for Neurodegenerative Diseases (DE)
- Humboldt-Universität zu Berlin (DE)
- Zimmer Biomet (Germany) (DE)
- Natural and Medical Sciences Institute (DE)
- German Centre for Cardiovascular Research (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Medizinische Universität Lausitz - Carl Thiem (DE)
- Freie Universität Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
- University of Tübingen (DE)
Publication Details
- Journal
- The Oncologist
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1093/oncolo/oyae268
- Citations
- 10
- Primary Topic
- Cancer-related cognitive impairment studies
- Type
- article
- Field-Weighted Citation Impact
- 4.19
Funders
- European Federation of Pharmaceutical Industries and Associations
- European Commission
- Deutsche Forschungsgemeinschaft
- Center for Stroke Research Berlin