Microbiological effect of different intracanal medicaments

The effect of Triple antibiotic paste (TAP), Modified triple antibiotic paste (MTAP) and its combination with Himalayan pink rock salt (HPRS) against Enterococcus faecalis is of interest to dentists. Intracanal medicaments were placed on specimens infected with EF and incubated. Antibacterial efficacy was evaluated by colony forming unit method on the 1st, 3rd, and 7th day. MTAP + HPRS showed the best results against E. faecalis on days 1 and 3 which were statistically significant. All subgroups showed zero colonies on day 7. HPRS combined with TAP/MTAP showed more antibacterial activity than TAP/MTP used without HPRS as intracanal medicament due to its synergistic effect. Hence, a modified triple antibiotic mixed with Himalayan pink rock salt can be used as a potential intracanal medicament with 2% Chlorhexidine.

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Publication Details

Journal
Bioinformation
Published
2024-08-31
DOI
https://doi.org/10.6026/973206300200893
Primary Topic
Neurological Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
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article

Microbiological effect of different intracanal medicaments

Rajan Dhawan, Jayata Dhawan, Shivani Dhawan, Aiswarya Ajith et al.
Bioinformation
Neurological Disease Mechanisms and Treatments
article

Microbiological effect of different intracanal medicaments

Rajan Dhawan, Jayata Dhawan, Shivani Dhawan, Aiswarya Ajith, Dikshant Tayal
article en

Abstract

The effect of Triple antibiotic paste (TAP), Modified triple antibiotic paste (MTAP) and its combination with Himalayan pink rock salt (HPRS) against Enterococcus faecalis is of interest to dentists. Intracanal medicaments were placed on specimens infected with EF and incubated. Antibacterial efficacy was evaluated by colony forming unit method on the 1st, 3rd, and 7th day. MTAP + HPRS showed the best results against E. faecalis on days 1 and 3 which were statistically significant. All subgroups showed zero colonies on day 7. HPRS combined with TAP/MTAP showed more antibacterial activity than TAP/MTP used without HPRS as intracanal medicament due to its synergistic effect. Hence, a modified triple antibiotic mixed with Himalayan pink rock salt can be used as a potential intracanal medicament with 2% Chlorhexidine.

BioinformationVol. 20(8)
Openalex Percentile: Top 80%
Neurological Disease Mechanisms and Treatments
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