The Onerous task of managing paroxysmal nocturnal hemoglobinuria in a Low resource setting: a case report. A hematologist’s experience
As part of the diagnostic workup for patients presenting with recurrent hemolytic anemia and thrombosis in unusual sites, clinicians should include PNH on the list of differential diagnoses. Effort should be taken to characterize the red urine reported on the urine dipstick as blood/hemoglobin by microscopy to differentiate hematuria and hemoglobinuria and order for flow cytometry as this has implications on patient management.
Authors
- Emmanuel Seremba (ORCID: https://orcid.org/0000-0001-5371-2464)
- Madeleine Verhovsek (ORCID: https://orcid.org/0000-0002-5022-9765)
- Christine Sekaggya‐Wiltshire (ORCID: https://orcid.org/0000-0001-9247-2950)
- David Enoch Kawalya (ORCID: https://orcid.org/0000-0002-9891-8965)
- Richard Mutyabule
- Henry Ddungu (ORCID: https://orcid.org/0000-0002-0912-2691)
- Musa K. Waiswa
Institutions
- Brigham and Women's Hospital (US)
- Lancet Laboratories (ZA)
- Uganda Cancer Institute (UG)
- Makerere University (UG)
- McMaster University (CA)
Publication Details
- Journal
- African Health Sciences
- Published
- 2024-10-06
- DOI
- https://doi.org/10.4314/ahs.v24i3.53
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00