The utility of Insulin Like Growth Factor Binding Proteins (IGFBPs-1, 2, 3) with genes expression in resistance to Imatinib and Nilotinib in chronic myeloid leukemia: a pilot study from Delta Egypt
IGFBP-1 gene expression and its serum were significantly correlated with resistance. It is currently recommended that IGF-receptor inhibitors be developed and utilized. We are hoping to optimize the cure rate for CML treated with TKIs.
Authors
- Mostafa Abdelhakiem (ORCID: https://orcid.org/0000-0001-5346-6339)
- Shaimaa El‐Ashwah (ORCID: https://orcid.org/0000-0003-2210-1534)
- Ramy Abbas
- Maha Saif (ORCID: https://orcid.org/0000-0002-4163-7820)
- Heidi Elkerdawy
- Ahmed EL-Sebaie (ORCID: https://orcid.org/0000-0003-1061-4658)
- Mohamed El-Ghonemy (ORCID: https://orcid.org/0000-0003-1192-7162)
- Nadia El Menshawy
Institutions
- Mansoura University (EG)
Publication Details
- Journal
- African Health Sciences
- Published
- 2024-10-06
- DOI
- https://doi.org/10.4314/ahs.v24i3.26
- Primary Topic
- Chronic Myeloid Leukemia Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00