In-vitro scientific validation of anti-inflammatory activity of Punica granatum L. on Leukemia monocytic cell line
Our findings indicate that no cytotoxicity was observed after the treatment of THP-1 cells with PPM (25-400 µg/ml), but at higher concentration (400µg/ml), the cell viability decreased to 84% and attenuated the expression level of inflammatory cytokines. The inhibitory effect of the extract on pro-inflammatory factors production may provide a theoretical source on upcoming treatment of inflammation.
Authors
- Sushil Kumar Middha
- Talambedu Usha (ORCID: https://orcid.org/0000-0003-1903-6268)
- Khushbu Nishad
- Sharmistha Dutta (ORCID: https://orcid.org/0009-0006-0721-3887)
- Nijalingappa Ramesh
Institutions
- Lakshmibai National Institute of Physical Education (IN)
- Department of Biotechnology (IN)
- REVA University (IN)
Publication Details
- Journal
- African Health Sciences
- Published
- 2024-10-06
- DOI
- https://doi.org/10.4314/ahs.v24i3.17
- Citations
- 1
- Primary Topic
- Pomegranate: compositions and health benefits
- Type
- article
- Field-Weighted Citation Impact
- 0.31
Funders
- Department of Science and Technology, Ministry of Science and Technology, India