JAK2 mutational status and the contribution of TERT and JAK2 polymorphisms to the occurrence of myeloproliferative neoplasms in Eastern Morocco

The JAK2 mutational status and its allelic burden in Eastern Morocco are consistent with previous studies. The JAK2 46/1 haplotype was strongly associated with MPN. However, unlike other previously studied populations, the TERT polymorphism rs2736100 has no effect on the occurrence of MPN in our population.

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Journal
African Health Sciences
Published
2024-10-06
DOI
https://doi.org/10.4314/ahs.v24i3.18
Primary Topic
Myeloproliferative Neoplasms: Diagnosis and Treatment
Type
article
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article

JAK2 mutational status and the contribution of TERT and JAK2 polymorphisms to the occurrence of myeloproliferative neoplasms in Eastern Morocco

Khalid Serraj, Mohammed Bellaoui, Majida Charif, Meryem Ouarzane et al.
African Health Sciences
Myeloproliferative Neoplasms: Diagnosis and Treatment
article

JAK2 mutational status and the contribution of TERT and JAK2 polymorphisms to the occurrence of myeloproliferative neoplasms in Eastern Morocco

Khalid Serraj, Mohammed Bellaoui, Majida Charif, Meryem Ouarzane, Karam Yahya Belmokhtar, Saida Lhousni, Manal Elidrissi Errahhali, Mounia Elidrissi Errahhali, N. Al Attar, Siham Hamaz, Redouane Boulouiz, Zaina Sidqi, Houda Bachir, Habiba Alaoui, Rachida Bouagaga
article en

Abstract

The JAK2 mutational status and its allelic burden in Eastern Morocco are consistent with previous studies. The JAK2 46/1 haplotype was strongly associated with MPN. However, unlike other previously studied populations, the TERT polymorphism rs2736100 has no effect on the occurrence of MPN in our population.

African Health SciencesVol. 24(3)
Mohamed I University (MA), Centre Hospitalo-Universitaire Mohammed VI d'Oujda (MA)
Openalex Percentile: Top 70%
Myeloproliferative Neoplasms: Diagnosis and Treatment
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