Adenomatous Polyposis Coli Gene Mutations, Risk Factors, and Long-term Outcomes Associated With Desmoid Tumors in Patients With Familial Adenomatous Polyposis After Colectomy in Japan
Adenomatous polyposis coli gene mutation sites alone were not considered a factor for delaying or avoiding colectomy to prevent desmoid tumors in Japanese patients with familial adenomatous polyposis. The timing of colectomy and careful surveillance should be considered for managing patients at a high risk of developing desmoid tumors. Desmoid tumors in patients with familial adenomatous polyposis did not significantly impact prognosis, and pharmacological treatments are important for disease control.
Authors
- Mayu Sakata (ORCID: https://orcid.org/0000-0003-0802-8641)
- Hiroya Takeuchi
- Hirotoshi Kikuchi (ORCID: https://orcid.org/0000-0002-1776-1020)
- Kyota Tatsuta (ORCID: https://orcid.org/0000-0001-8513-0039)
- Toshiya Akai
- Tadahiro Kojima (ORCID: https://orcid.org/0000-0001-9310-2329)
- Moriya Iwaizumi (ORCID: https://orcid.org/0000-0002-2629-0830)
- Yoshifumi Morita (ORCID: https://orcid.org/0000-0001-6940-2487)
- Yoshihiro Hiramatsu (ORCID: https://orcid.org/0000-0001-9874-5059)
- Kiyotaka Kurachi (ORCID: https://orcid.org/0000-0003-3967-5139)
- Kosuke Sugiyama (ORCID: https://orcid.org/0000-0002-1453-6573)
Institutions
- Hamamatsu University School of Medicine (JP)
- DMG Mori (Japan) (JP)
Publication Details
- Journal
- Journal of Clinical Gastroenterology
- Published
- 2024-10-11
- DOI
- https://doi.org/10.1097/mcg.0000000000002071
- Primary Topic
- Soft tissue tumor case studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00