CircWDR37 promotes hepatocellular carcinoma tumorigenesis by mediating the miR-646/TRAF4 regulatory pathway
CircWDR37 exerted an oncogenic effect in HCC by sponging miR-646 to up-regulate TRAF4 expression. Our finding elucidates a novel 'circWDR37-miR-646-TRAF4' regulatory axis in HCC and provides a promising target for HCC treatment.
Authors
- Yongpeng He (ORCID: https://orcid.org/0009-0009-6096-6935)
- Jie Zhou (ORCID: https://orcid.org/0000-0002-6002-291X)
- Qing Hua Zhang (ORCID: https://orcid.org/0000-0002-6595-8995)
- Zhu Zhu (ORCID: https://orcid.org/0000-0003-3952-8665)
- Xi Zhang (ORCID: https://orcid.org/0009-0007-1790-5884)
- Wenli Peng
Institutions
- Guiyang College of Traditional Chinese Medicine (CN)
- Guizhou Provincial People's Hospital (CN)
- Chongqing Cancer Hospital (CN)
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Pathology - Research and Practice
- Published
- 2024-10-16
- DOI
- https://doi.org/10.1016/j.prp.2024.155658
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00