Outcomes with revascularisation versus conservative management of participants with 3-vessel coronary artery disease in the ISCHEMIA trial
In participants with 3V-CAD, REV (either PCI or CABG) was associated with a lower 4-year CV death/MI rate and improved quality of life, with similar results for PCI versus CON and CABG versus CON. The differences in all-cause mortality between REV and CON were small with wide confidence intervals. (ClinicalTrials.gov: NCT01471522).
Authors
- John A. Spertus (ORCID: https://orcid.org/0000-0002-2839-2611)
- Daniel B. Mark (ORCID: https://orcid.org/0000-0001-6340-8087)
- Grace L. Rhodes
- Harmony R. Reynolds (ORCID: https://orcid.org/0000-0003-0284-0655)
- Gregg W. Stone (ORCID: https://orcid.org/0000-0002-3416-8210)
- Yifan Xu (ORCID: https://orcid.org/0009-0006-3655-1025)
- David J. Maron (ORCID: https://orcid.org/0000-0002-4867-8588)
- Sripal Bangalore (ORCID: https://orcid.org/0000-0001-9485-0652)
- Rebecca Anthopolos (ORCID: https://orcid.org/0000-0002-7251-7792)
- Harvey D. White (ORCID: https://orcid.org/0000-0001-7712-6750)
- Philip G. Jones (ORCID: https://orcid.org/0000-0002-7136-4464)
- Judith S. Hochman (ORCID: https://orcid.org/0000-0002-5889-5981)
- Stephen Edward Fremes (ORCID: https://orcid.org/0000-0003-1723-3049)
- Sean M. O’Brien
Institutions
- Sunnybrook Health Science Centre (CA)
- University of Toronto (CA)
- Cardiovascular Institute of the South (US)
- Health Sciences Centre (CA)
- Clinical Research Institute (US)
- Saint Luke's Hospital (US)
- New York University (US)
- University of Missouri–Kansas City (US)
- Stanford University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- EuroIntervention
- Published
- 2024-10-01
- DOI
- https://doi.org/10.4244/eij-d-24-00240
- Citations
- 6
- Primary Topic
- Coronary Interventions and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 3.44
Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- National Heart, Lung, and Blood Institute
- National Center for Advancing Translational Sciences