Metabolomic Profiling and Network Toxicology: Mechanistic Insights into Effect of Gossypol Acetate Isomers in Uterine Fibroids and Liver Injury

(-)-gossypol acetate and (+)-gossypol acetate play positive roles in the treatment and prevention of uterine fibroids. Gossypol optical isomers cause liver damage through multiple targets and pathways.

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Publication Details

Journal
Pharmaceuticals
Published
2024-10-12
DOI
https://doi.org/10.3390/ph17101363
Citations
3
Primary Topic
Research in Cotton Cultivation
Type
article
Field-Weighted Citation Impact
1.80

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article

Metabolomic Profiling and Network Toxicology: Mechanistic Insights into Effect of Gossypol Acetate Isomers in Uterine Fibroids and Liver Injury

Zishuo Liu, Hui Zhang, Jun Yao
3 citations
Pharmaceuticals
Research in Cotton Cultivation
1.80
article

Metabolomic Profiling and Network Toxicology: Mechanistic Insights into Effect of Gossypol Acetate Isomers in Uterine Fibroids and Liver Injury

Zishuo Liu, Hui Zhang, Jun Yao
article en
3 citations

Abstract

(-)-gossypol acetate and (+)-gossypol acetate play positive roles in the treatment and prevention of uterine fibroids. Gossypol optical isomers cause liver damage through multiple targets and pathways.

PharmaceuticalsVol. 17(10)
Xinjiang Medical University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 13%
Research in Cotton Cultivation
1.80
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