The guidelines for clinical practice for carriers of germline mutations in the Lynch syndrome predisposition genes MLH1, MSH2, MSH6, PMS2 and large deletions of EPCAM (4.2024)

The guidelines for clinical practice for carriers of pathogenic variants in clinically relevant genes predisposing to Lynch syndrome and colorectal cancer define the steps of primary and secondary prevention that should be provided to the individuals at high risk of developing hereditary cancer in the Czech Republic. The drafting of the guidelines was organized by the Oncogenetics Working Group of the Society for Medical Genetics and Genomics of J. E. Purkyně Czech Medical Society, in cooperation with representatives of oncology, oncogynecology, and gastroenterology. The guidelines are based on the current recommendations of the National Comprehensive Cancer Network (NCCN), European Society of Medical Oncology (ESMO) and take into account the capacity of the Czech healthcare system.

Authors

Zdeňka Vlčková
Václava Curtisová (ORCID: https://orcid.org/0000-0001-7829-2881)
Markéta Palácová
Zdeněk Kleibl (ORCID: https://orcid.org/0000-0003-2050-9667)
Alena Puchmajerová
Kamila Veselá (ORCID: https://orcid.org/0000-0003-0270-3845)
Jana Soukupová (ORCID: https://orcid.org/0000-0003-2413-1542)
Markéta Janatová (ORCID: https://orcid.org/0000-0003-2816-6769)
H. Štěpánková (ORCID: https://orcid.org/0000-0002-4051-2495)
Monika Koudová (ORCID: https://orcid.org/0000-0002-1323-4936)
Šárka Vilímová
Petra Kleiblová (ORCID: https://orcid.org/0000-0002-4806-9854)
Ilja Tachecí (ORCID: https://orcid.org/0000-0003-3583-2651)
Ondřej Urban (ORCID: https://orcid.org/0000-0002-6705-7912)
Lenka Foretová (ORCID: https://orcid.org/0000-0003-0494-2620)
Vít Weinberger (ORCID: https://orcid.org/0000-0003-4858-1951)
Mária Šenkeříková
Martina Zimovjanová (ORCID: https://orcid.org/0000-0001-5261-3501)
Ondřej Havránek (ORCID: https://orcid.org/0000-0001-5826-3557)
Ivan Šubrt (ORCID: https://orcid.org/0000-0003-2540-0863)
Jří Presl
Oľga Dubová (ORCID: https://orcid.org/0009-0006-7185-550X)
Pavel Tesner (ORCID: https://orcid.org/0000-0001-6033-2953)
Michal Zikán (ORCID: https://orcid.org/0000-0001-5266-8895)
David Cibula (ORCID: https://orcid.org/0000-0001-6387-9356)
Katarína Petráková
Michal Vočka (ORCID: https://orcid.org/0000-0002-9386-657X)
Věra Krutílková
Jan Novotný
Anna Germanová
Markéta Hudcová
Sviatlana Paulich
Zuzana Šimková
Markéta Hojsáková

Publication Details

Journal: Klinicka onkologie
Published: 2024-10-14
DOI: https://doi.org/10.48095/ccko2024384
Primary Topic: Genetic factors in colorectal cancer
Type: article
Field-Weighted Citation Impact: 0.00

The guidelines for clinical practice for carriers of germline mutations in the Lynch syndrome predisposition genes MLH1, MSH2, MSH6, PMS2 and large deletions of EPCAM (4.2024)

Zdeňka Vlčková, Václava Curtisová, Markéta Palácová, Zdeněk Kleibl, Alena Puchmajerová, Kamila Veselá, Jana Soukupová, Markéta Janatová, H. Štěpánková, Monika Koudová, Šárka Vilímová, Petra Kleiblová, Ilja Tachecí, Ondřej Urban, Lenka Foretová, Vít Weinberger, Mária Šenkeříková, Martina Zimovjanová, Ondřej Havránek, Ivan Šubrt, Jří Presl, Oľga Dubová, Pavel Tesner, Michal Zikán, David Cibula, Katarína Petráková, Michal Vočka, Věra Krutílková, Jan Novotný, Anna Germanová, Markéta Hudcová, Sviatlana Paulich, Zuzana Šimková, Markéta Hojsáková

October 14, 2024article en

The guidelines for clinical practice for carriers of germline mutations in the Lynch syndrome predisposition genes MLH1, MSH2, MSH6, PMS2 and large deletions of EPCAM (4.2024)

Authors

Publication Details

The guidelines for clinical practice for carriers of germline mutations in the Lynch syndrome predisposition genes MLH1, MSH2, MSH6, PMS2 and large deletions of EPCAM (4.2024)

The guidelines for clinical practice for carriers of germline mutations in the Lynch syndrome predisposition genes MLH1, MSH2, MSH6, PMS2 and large deletions of EPCAM (4.2024)

Abstract

Ask Laika to Summarize, Analyze, and Connect papers live on the map.