Role of immune cells in mediating the effect of gut microbiota on Hashimoto’s thyroiditis: a 2-sample Mendelian randomization study
In conclusion, we presented causal associations between the EM CD4 + T cell-mediated gut microbiota and HT, as inferred from the MR findings derived from extensive aggregated GWAS data. Our research offers guidance and direction for treating and preventing HT.
Authors
- Tong-Xin Zhang
- Zhendan Zhao
- Xiao‐Qing Pei
- Yuehua Gao (ORCID: https://orcid.org/0000-0002-8934-7128)
- Huawei Zhang (ORCID: https://orcid.org/0000-0002-0641-4680)
- Wenhao Wang (ORCID: https://orcid.org/0000-0002-5321-3857)
- Jingyu Liu (ORCID: https://orcid.org/0000-0002-1724-7523)
Institutions
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2024-10-14
- DOI
- https://doi.org/10.3389/fmicb.2024.1463394
- Citations
- 3
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.65
Funders
- Shandong First Medical University