A RANDOMIZED, OPEN LABELLED, CONTROLLED EQUIVALENCE PILOT DRUG TRIAL TO EVALUATE EFFECT OF POLYHERBAL FORMULATIONS, EFFICACY AND SAFETY OF MODIFIED PANCHAKARMA TREATMENT PLAN OBETOX IN PATIENTS WITH OBESITY (MEDOROG).

A chronic complex diseases with excessive fat deposition is called as Obesity. It an lead to many metabolic disease like Type II diabetes, heart diseases, thyroid, hypertension, increased bloos cholesterol level, liver disease, sleep apnoea and certain cancers. It can lead to increase the risk of co morbid conditions specially heart diseases. Weight loss can improve or prevent many health issues related to Obesity. Ayurveda says that Obesity is Vikrita Vriddhi (Abnormal increase) of Medodhatu (Fatty Tissue).Aims and Objective- This study was planned to evaluate the efficacy of Ayurvedic treatment Tab Mednil, Tab Suhruday & Obetox Treatment Plan in the treatment of Obesity (Medorog) and to assess the change in various biochemical markers.Method- This is a proof-of-concept study in which a sample size of 60 participants (30 in each group) was considered sufficient to achieve the study objectives. Participants were randomly assigned to two groups according to a computer-generated randomization list.Results- The results show that participants observed a lighter body image, more energy and enthusiasm, and a reduction in obesity-related complications, in terms of weight, H/W ratio, BMI and lipid profile.Conclusion- Obetox protocol along with herbal remedies gives significant results in the Obesity.