(E)-5-hydroxy-7-methoxy-3-(2-hydroxybenzyl)-4-chromanone, a Major Homoisoflavonoid, Attenuates Free Fatty Acid-Induced Hepatic Steatosis by Activating AMPK and PPARα Pathways in HepG2 Cells
HMC inhibits lipid accumulation and promotes fatty acid oxidation by AMPK and PPARα pathways in free fatty acid-treated HepG2 cells, thereby attenuating hepatic steatosis.
Authors
- Ji-Sook Han (ORCID: https://orcid.org/0000-0002-6282-6815)
- Jae-Eun Park (ORCID: https://orcid.org/0000-0002-9140-5518)
Institutions
- Pusan National University (KR)
Publication Details
- Journal
- Nutrients
- Published
- 2024-10-14
- DOI
- https://doi.org/10.3390/nu16203475
- Citations
- 1
- Primary Topic
- Peroxisome Proliferator-Activated Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- National Research Foundation
- National Research Foundation of Korea