Treatment of polyethylene microplastics degraded by ultraviolet light irradiation causes lysosome-deregulated cell death
This study unveils that UV-induced degradation of PE results in cell death attributed to lysosomal dysfunction. The findings presented herein provide novel insights into the effects of surface-degraded MPs on biological responses.
Authors
- Yasuo M Tsutsumi (ORCID: https://orcid.org/0000-0002-1997-082X)
- Haruyasu Asahara (ORCID: https://orcid.org/0000-0002-1808-7373)
- Yuya Haga (ORCID: https://orcid.org/0000-0003-4148-2256)
- Hirofumi Tsujino (ORCID: https://orcid.org/0000-0003-0926-5876)
- Yudai Ikuno
- Kazuma Higashisaka (ORCID: https://orcid.org/0000-0001-9473-8302)
- Sota Manabe (ORCID: https://orcid.org/0009-0001-0308-7872)
Institutions
- Toneyama National Hospital (JP)
- The University of Osaka (JP)
Publication Details
- Journal
- Scientific Reports
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1038/s41598-024-74800-y
- Citations
- 9
- Primary Topic
- Microplastics and Plastic Pollution
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- Sumitomo Foundation
- Japan Agency for Medical Research and Development
- Environmental Restoration and Conservation Agency
- Ministry of Health, Labour and Welfare
- Japan Society for the Promotion of Science