The association between non-alcoholic liver fatty disease and coronary artery calcification: a two-sample Mendelian randomization study
Our two-sample MR analysis did not support that there is a causal association between NAFLD and CAC at genetic level. The association between NAFLD and CAC reported in some previous observational studies may rely on NAFLD complicated with metabolic disorders, rather than being directly linked to the hepatic steatosis.
Authors
- Xieraili Tiemuerniyazi
- Ziang Yang (ORCID: https://orcid.org/0000-0003-2626-674X)
- Lianxin Chen
- Wei Feng (ORCID: https://orcid.org/0000-0003-1157-8302)
- Shengkang Huang (ORCID: https://orcid.org/0009-0008-9714-3548)
- Yifeng Nan
- Yangwu Song (ORCID: https://orcid.org/0000-0003-3604-8383)
- Liaoming He
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
Publication Details
- Journal
- European Journal of Preventive Cardiology
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1093/eurjpc/zwae336
- Citations
- 6
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.32
Funders
- Ministry of Science and Technology of the People's Republic of China
- National Key Research and Development Program of China