Establishment and Characterization of a Novel Pleuropulmonary Blastoma Cell Line
Our KCMC-PPB-1 is the first genuine, molecularly characterized PPB cell line. The cell line is transplantable to nu/nu mice; therefore, it is suitable for a preclinical model for new drug development. The cytotoxicity assay demonstrated that bortezomib is active in the current PPB model.
Authors
- Masafumi Seki (ORCID: https://orcid.org/0000-0001-5414-8148)
- Toshiji Nishi
- Tetsuomi Suzuki
- Kenji Kurosawa (ORCID: https://orcid.org/0000-0002-6817-7748)
- Hiroaki Goto (ORCID: https://orcid.org/0000-0001-6737-1509)
- Keisuke Kato (ORCID: https://orcid.org/0000-0002-0135-5431)
- Yumi Ito (ORCID: https://orcid.org/0000-0001-9871-8931)
- Masahiro Tsuchida
- Asami Noda
- Mio Tanaka (ORCID: https://orcid.org/0000-0003-1122-7457)
- Ai Yoshimi (ORCID: https://orcid.org/0000-0002-8642-1214)
- Noriyuki Nagahara (ORCID: https://orcid.org/0000-0002-4476-5748)
- Noriko Aida (ORCID: https://orcid.org/0000-0002-2776-2115)
- Junko Takita (ORCID: https://orcid.org/0000-0002-2452-6520)
- Hisato Kigasawa
- Norihiko Kitagawa (ORCID: https://orcid.org/0000-0002-1629-5857)
- Masato Shinkai (ORCID: https://orcid.org/0000-0002-7757-6441)
- Yasunori Toyoda
- Yukichi Tanaka
Institutions
- Tsurumi University (JP)
- Kyoto University (JP)
- Kanagawa Children's Medical Center (JP)
- Ibaraki Children's Hospital (JP)
- The University of Tokyo (JP)
- Nippon Medical School (JP)
Publication Details
- Journal
- Genes Chromosomes and Cancer
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1002/gcc.23276
- Primary Topic
- Congenital Diaphragmatic Hernia Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science