The spatial impact of a Western diet in enriching Galectin-1-regulated Rho, ECM, and SASP signaling in a novel MASH-HCC mouse model
WD intake significantly influences vital cellular processes involved in Gal-1-mediated signaling, including Rho signaling and ECM remodeling, in the tumor microenvironment, thereby contributing to the development of MASH-HCC.
Authors
- Tahereh Setayesh (ORCID: https://orcid.org/0000-0002-1770-208X)
- Yu‐Jui Yvonne Wan (ORCID: https://orcid.org/0000-0003-2243-7759)
- Ying Hu
- Farzam Vaziri (ORCID: https://orcid.org/0000-0001-7788-2548)
- Dongguang Wei
Institutions
- University of California Davis Medical Center (US)
Publication Details
- Journal
- Biomarker Research
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1186/s40364-024-00660-3
- Citations
- 7
- Primary Topic
- Galectins and Cancer Biology
- Type
- article
- Field-Weighted Citation Impact
- 1.68
Funders
- National Institutes of Health
- University of California, Davis
- Comprehensive Cancer Center, University of California, Davis