Difficulties in Diagnosing Peritoneal Mesothelioma (Rare Clinical Case)

The goal of the study was to draw the attention of surgeons, angiosurgeons, infectious disease specialists and oncologists to non-standard predictors of peritoneal mesothelioma development and peculiarities of its diagnostics. The artice presents the analysis of publications on the diagnosis of malignant peritoneal mesothelioma and our own clinical observation with unusual disease debut: cervical lymphadenopathy, thrombosis of the branches of the superior vena cava, bilateral exudative pleurisy. Diagnostic algorithm of peritoneal mesothelioma consists of analyzing the results of clinical examination with sequential application of ultrasound, multispiral computed tomography of the neck, thoracic, abdominal and small pelvis organs with intravenous bolus contrast (MSCTAG), positron emission tomography combined with computed tomography (PET/CT). Endovideoscopy with histologic and immunohistochemical examination of peritoneal biopsy specimens using mesothelial lineage antibodies and epithelial markers is the final and clarifying method of diagnostics of malignant peritoneal mesothelioma.