ApaI Polymorphism in the Vitamin D Receptor Gene Decreases the Risk of Perianal Fistulas in Crohn’s Disease
The aa genotype of the <i>ApaI</i> SNP in the <i>VDR</i> gene is associated with a lower risk of perianal fistulas in CD and a reduced expression of fibrotic and inflammatory markers in intestinal fibroblasts.
Authors
- Sara Calatayud (ORCID: https://orcid.org/0000-0001-9675-2423)
- Dulce C. Macias-Ceja (ORCID: https://orcid.org/0000-0002-1957-5854)
- Joaquín Hinojosa (ORCID: https://orcid.org/0000-0002-2157-9328)
- D Ortiz‐Masiá (ORCID: https://orcid.org/0000-0002-7924-9962)
- Juan V. Llau (ORCID: https://orcid.org/0000-0002-9322-5959)
- Laura Gisbert-Ferrándiz (ORCID: https://orcid.org/0000-0002-2007-8716)
- M D Barrachina (ORCID: https://orcid.org/0000-0002-4332-2929)
- Jesús Cosín‐Roger (ORCID: https://orcid.org/0000-0002-2468-4908)
Institutions
- Universitat de València (ES)
- Centro de Investigación Biomédica en Red (ES)
- Hospital de Manises (ES)
Publication Details
- Journal
- Nutrients
- Published
- 2024-10-14
- DOI
- https://doi.org/10.3390/nu16203485
- Citations
- 2
- Primary Topic
- Eosinophilic Esophagitis
- Type
- article
- Field-Weighted Citation Impact
- 1.15
Funders
- European Commission
- Generalitat Valenciana
- Ministerio de Ciencia e Innovación
- European Regional Development Fund
- Agencia Estatal de Investigación