Low‐dose estrogen release from silastic capsule enhanced flap wound healing in an animal model
In summary, the study showed that an estrogen silastic capsule maintained physiological estrogen levels and improved superficial perfusion, thereby reducing dermal hypoxia, and cell death in a mouse random pattern skin flap model. Although no significant promotion of angiogenesis was observed, the study suggests that appropriate estrogen supplements could enhance flap wound recovery.
Authors
- Kuang‐Ling Ou (ORCID: https://orcid.org/0000-0001-9536-2677)
- Shih‐Ming Huang (ORCID: https://orcid.org/0000-0001-9305-921X)
- Kai‐Chieh Chou (ORCID: https://orcid.org/0000-0002-9772-9310)
- Chun‐Ting Chen (ORCID: https://orcid.org/0000-0003-1118-7221)
- Yi‐Wen Wang
Institutions
- Tri-Service General Hospital (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- International Wound Journal
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1111/iwj.70083
- Citations
- 2
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.50
Funders
- Medical Affairs Bureau