Synthesis of Trifluoromethylselenolated Spiro[5.5]trienones/Spiro[4.5]trienones via Electrophilic Trifluoromethylselenolation Cyclization and Dearomatization
Abstract An expedient strategy for the construction of trifluoromethylselenolated spiro[5.5]trienones/spiro[4.5]trienones through a cascade electrophilic trifluoromethylselenolation cyclization and dearomatization has been developed. This sequential process was induced by N ‐trifluoromethylselenophthalimide (Phth‐SeCF 3 ), which was an efficient electrophilic trifluoromethylselenolation reagent. This approach has the feature of mild conditions, broad substrate scope, and high functional group tolerance.
Authors
- Xuefang Shang (ORCID: https://orcid.org/0000-0003-1280-1553)
- Shujun Chao (ORCID: https://orcid.org/0000-0001-7164-4813)
- Jiaqi Niu (ORCID: https://orcid.org/0000-0002-1121-8457)
- Jiacheng Li (ORCID: https://orcid.org/0000-0002-6996-4778)
- Jia Wang (ORCID: https://orcid.org/0000-0002-6237-8434)
- Lixia Liu (ORCID: https://orcid.org/0000-0001-7116-8722)
- Yunhui Yan (ORCID: https://orcid.org/0000-0002-6961-6765)
- Mingjiang Geng
Institutions
- Henan Medical University (CN)
Publication Details
- Journal
- Advanced Synthesis & Catalysis
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1002/adsc.202401099
- Citations
- 9
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Xinxiang Medical University