A rare case of a large solid pseudopapillary neoplasm with extensive liver metastasis

Solid pseudopapillary neoplasms (SPNs) are uncommon pancreatic tumors that primarily affect young females. We report a case of a 24-year-old female diagnosed with SPN and liver metastasis during a routine examination. Imaging revealed an 8-cm pancreatic mass with multiple liver metastases. Histopathology confirmed SPN. Subsequent next-generation sequencing revealed a <i>CTNNB1</i> mutation. The patient underwent a total pancreatectomy with splenectomy, right hemihepatectomy, and intraoperative radiofrequency ablation. Two years after the surgery, she remained complication-free. She is under regular surveillance. This case underscores the importance of early detection and comprehensive management of SPN.

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Publication Details

Journal
Annals of Hepato-Biliary-Pancreatic Surgery
Published
2024-10-14
DOI
https://doi.org/10.14701/ahbps.24-147
Primary Topic
Medical Imaging and Pathology Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

A rare case of a large solid pseudopapillary neoplasm with extensive liver metastasis

Ji Hae Nahm, Jung Min Lee, Joon Seong Park, Jun Hyung Kim et al.
Annals of Hepato-Biliary-Pancreatic Surgery
Medical Imaging and Pathology Studies
article

A rare case of a large solid pseudopapillary neoplasm with extensive liver metastasis

Ji Hae Nahm, Jung Min Lee, Joon Seong Park, Jun Hyung Kim, Hyung Sun Kim
article en

Abstract

Solid pseudopapillary neoplasms (SPNs) are uncommon pancreatic tumors that primarily affect young females. We report a case of a 24-year-old female diagnosed with SPN and liver metastasis during a routine examination. Imaging revealed an 8-cm pancreatic mass with multiple liver metastases. Histopathology confirmed SPN. Subsequent next-generation sequencing revealed a <i>CTNNB1</i> mutation. The patient underwent a total pancreatectomy with splenectomy, right hemihepatectomy, and intraoperative radiofrequency ablation. Two years after the surgery, she remained complication-free. She is under regular surveillance. This case underscores the importance of early detection and comprehensive management of SPN.

Annals of Hepato-Biliary-Pancreatic SurgeryVol. 29(1)
Seoul National University (KR), Yonsei University (KR), National Health Insurance Service Ilsan Hospital (KR), Gangnam Severance Hospital (KR), Hallym University Dongtan Sacred Heart Hospital (KR), National Health Insurance Service (KR)
Ministry of Health and Welfare, Korea Health Industry Development Institute
Zero hunger
Openalex Percentile: Top 67%
Medical Imaging and Pathology Studies
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