Reference equations for DLNO and DLCO in Mexican Hispanics: influence of altitude and race
Mexican Hispanics born and raised at 2240 m exhibit higher DLCO and DLNO compared with lowlanders. Including race as a covariate in reference equations lowers the RMSE for DLNO, DLCO and KNO and reduces FPR and FNR compared with race-neutral models. This study highlights the need for altitude-specific and race-specific reference equations to improve pulmonary function assessments across diverse populations.
Authors
- Alejandro Reyes-García (ORCID: https://orcid.org/0009-0002-0044-9978)
- Mario H. Vargas (ORCID: https://orcid.org/0000-0002-8420-980X)
- Laura Gochicoa‐Rangel (ORCID: https://orcid.org/0000-0003-3009-5867)
- Luis Torre‐Bouscoulet (ORCID: https://orcid.org/0000-0003-2183-7662)
- David Martínez Briseño (ORCID: https://orcid.org/0000-0002-8613-2658)
- Carlos Guzmán-Valderrábano (ORCID: https://orcid.org/0000-0002-8279-8903)
- Irma Lechuga-Trejo (ORCID: https://orcid.org/0000-0002-1296-6115)
- Gerald Stanley Zavorsky (ORCID: https://orcid.org/0000-0002-4473-1601)
- Ada De-Los-Santos-Martínez (ORCID: https://orcid.org/0009-0007-5553-7330)
Institutions
- Instituto Nacional de Enfermedades Respiratorias (MX)
- University of California, Davis (US)
Publication Details
- Journal
- BMJ Open Respiratory Research
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1136/bmjresp-2024-002341
- Citations
- 10
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 4.19