Antimicrobial and antioxidant activities of Bromelin Propolis Spray

The indiscriminate use of antibiotics over the last 60 years has led to the development of resistant strains, leading an urgent need for new treatments, new molecules or combinations of products, safety and effective. In this regard, propolis has been used in traditional medicine due its therapeutic effects, such as antibacterial, antifungal and antiseptic, tested in vitro, in vivo and clinically. The aim of this study is to evaluate the antimicrobial and antioxidant activities of a commercial oral flavoring product against bacterial strains of clinical interest from the upper respiratory tract. Bacteria sensitivity against Bromelin Propolis Sprayâ (BPS) was evaluated using macrodilution in broth and no turbid tubes plated on TSA to confirm the results. Tested bacteria were Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa. BPS showed antimicrobial activity for all tested strains and the MBC was 2.5mg/mL. Moreover, the antioxidant activity was determined by the ability to scavenge the stable radical DPPH. 0.007% of BPS showed the maximum antioxidant effect, of 6.63mM, which demonstrate its high antioxidant effect. Therefore, these results indicate that the commercial product BPS at 0.7% can be a potential candidate as adjuvant in antibiotic therapy for upper respiratory tract disorders, due possible antimicrobial effect and its high antioxidant potential.