<scp>POU2F2</scp> activates the Akt/<scp>mTOR</scp> signalling pathway and enhances B lymphocyte function during diabetic kidney disease by promoting <scp>PIK3CD</scp> transcription
This study demonstrates that POU2F2 mediates PIK3CD-dependent Akt/mTOR signalling activation, thus enhancing B lymphocyte function and promoting DKD progression.
Authors
- Haiqiao Yu
- Chenzhou Mao (ORCID: https://orcid.org/0009-0000-7579-9900)
- Xiaolin Zi (ORCID: https://orcid.org/0000-0002-5312-7158)
- Xiaoxia Li (ORCID: https://orcid.org/0000-0003-4900-8946)
- Shengjun Cao
Institutions
- Harbin Medical University (CN)
- Fourth Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Nephrology
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1111/nep.14404
- Citations
- 2
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 0.68