Identification of a 5-gene signature panel for the prediction of prostate cancer progression
Our study presents a new 5-gene signature panel that is associated with worse clinical prognosis and is elevated in prostate cancer metastasis on both protein and mRNA levels. Our 5-gene signature panel represents a potential modality for the prediction of prostate cancer progression towards the onset of metastasis.
Authors
- Sharon J. Pitteri (ORCID: https://orcid.org/0000-0002-3119-873X)
- Chia‐Nung Hung
- Shiqin Liu (ORCID: https://orcid.org/0000-0002-0818-6036)
- Michael A. Liss (ORCID: https://orcid.org/0000-0001-6978-1026)
- Arvind Muruganantham (ORCID: https://orcid.org/0000-0001-8395-4624)
- Michelle Shen (ORCID: https://orcid.org/0009-0005-4105-5766)
- James R. White (ORCID: https://orcid.org/0000-0002-7535-9179)
- Tim H.‐M. Huang (ORCID: https://orcid.org/0000-0001-5985-9176)
- Meghan A. Rice (ORCID: https://orcid.org/0000-0003-4578-0461)
- Chun-Liang Chen (ORCID: https://orcid.org/0000-0002-0755-7587)
- Kelsey Thompson
- Tanya Ivanova Stoyanova (ORCID: https://orcid.org/0000-0003-0119-9747)
- Fernando Jose Garcia-Marques (ORCID: https://orcid.org/0000-0002-2105-2905)
- Kenneth J. Pienta (ORCID: https://orcid.org/0000-0002-4138-2186)
- Zhao Zhang (ORCID: https://orcid.org/0000-0002-3757-8469)
- Abel Bermudez (ORCID: https://orcid.org/0009-0002-3235-5538)
Institutions
- Johns Hopkins University (US)
- University of California, Los Angeles (US)
- The University of Texas at San Antonio Health Science Center (US)
- Johns Hopkins Medicine (US)
- Urology San Antonio (US)
- Resphera Biosciences (US)
- The University of Texas Health Science Center (US)
- The University of Texas Health Science Center at Houston (US)
- Stanford University (US)
Publication Details
- Journal
- British Journal of Cancer
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1038/s41416-024-02854-w
- Citations
- 2
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.84
Funders
- National Institutes of Health
- National Cancer Institute