Risk of Suicidal Ideation or Attempts in Adolescents With Obesity Treated With GLP1 Receptor Agonists

In this study, adolescents with obesity prescribed a GLP1R had a lower incidence of suicidal ideation or attempts compared with matched patients not prescribed GLP1R who were treated with lifestyle intervention. These results suggest a favorable psychiatric safety profile of GLP1R in adolescents. The detected reduction in HRs for suicidal ideation among adolescents with obesity prescribed GLP1R suggests potential avenues for future research.

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Publication Details

Journal
JAMA Pediatrics
Published
2024-10-14
DOI
https://doi.org/10.1001/jamapediatrics.2024.3812
Citations
29
Primary Topic
Eating Disorders and Behaviors
Type
article
Field-Weighted Citation Impact
18.53
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article

Risk of Suicidal Ideation or Attempts in Adolescents With Obesity Treated With GLP1 Receptor Agonists

Liya Kerem, Joshua Stokar
29 citations
JAMA Pediatrics
Eating Disorders and Behaviors
18.53
article

Risk of Suicidal Ideation or Attempts in Adolescents With Obesity Treated With GLP1 Receptor Agonists

Liya Kerem, Joshua Stokar
article en
29 citations

Abstract

In this study, adolescents with obesity prescribed a GLP1R had a lower incidence of suicidal ideation or attempts compared with matched patients not prescribed GLP1R who were treated with lifestyle intervention. These results suggest a favorable psychiatric safety profile of GLP1R in adolescents. The detected reduction in HRs for suicidal ideation among adolescents with obesity prescribed GLP1R suggests potential avenues for future research.

JAMA PediatricsVol. 178(12)
Hebrew University of Jerusalem (IL), Hadassah Medical Center (IL)
Good health and well-being
Openalex Percentile: Top 0%
Eating Disorders and Behaviors
18.53
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