Gynaecomastia revealing amiodarone-induced hypergonadotropic hypogonadism: an overlooked complication?

This case highlights the causal relationship between prolonged amiodarone use and the development of hypogonadism.The underlying mechanism involves the destructive effect of amiodarone on testicular tissue, leading to primary hypogonadism through testicular atrophy.It is crucial to monitor patients for clinical signs of hypogonadism after prescribing amiodarone to ensure timely diagnosis and treatment of any resulting hypogonadism.

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Publication Details

Journal
European Journal of Case Reports in Internal Medicine
Published
2024-10-14
DOI
https://doi.org/10.12890/2024_004726
Citations
2
Primary Topic
Hormonal and reproductive studies
Type
article
Field-Weighted Citation Impact
0.72
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article

Gynaecomastia revealing amiodarone-induced hypergonadotropic hypogonadism: an overlooked complication?

Etienne Delgrange, Corinne Jonas, Lynda Vickya Bombil
2 citations
European Journal of Case Reports in Internal Medicine
Hormonal and reproductive studies
0.72
article

Gynaecomastia revealing amiodarone-induced hypergonadotropic hypogonadism: an overlooked complication?

Etienne Delgrange, Corinne Jonas, Lynda Vickya Bombil
article en
2 citations

Abstract

This case highlights the causal relationship between prolonged amiodarone use and the development of hypogonadism.The underlying mechanism involves the destructive effect of amiodarone on testicular tissue, leading to primary hypogonadism through testicular atrophy.It is crucial to monitor patients for clinical signs of hypogonadism after prescribing amiodarone to ensure timely diagnosis and treatment of any resulting hypogonadism.

European Journal of Case Reports in Internal MedicineVol. 11(11)
UCLouvain (BE)
Good health and well-being
Openalex Percentile: Top 25%
Hormonal and reproductive studies
0.72
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