Low penicillin susceptibility in <i>Streptococcus mitis/oralis</i> from bloodstream infections in pediatric populations

Existing research primarily focuses on specific populations, such as those with hematopathy or tumors, who experience <i>Streptococcus mitis/oralis</i> bacteremia. Limited studies have been conducted on the prevalence of bloodstream infections caused by <i>S. mitis/oralis</i> across the entire pediatric population. It was found that the contamination rate of <i>S. mitis/oralis</i> isolated from blood cultures was notably high in our study. Therefore, this study evaluated the clinical characteristics and drug resistance patterns of bloodstream infections caused by <i>S. mitis/oralis</i> across the entire pediatric populations, explicitly excluding cases of blood culture contamination. The observed low susceptibility rate to penicillin, coupled with the emergence of multi-drug-resistant strains, underscores the imperative for continuous monitoring of the evolving antimicrobial resistance in <i>S. mitis/oralis</i>.