Evaluating the Efficacy of Platelet-Rich Fibrin with Laser Biostimulation in Treatment of Gingival Recessions: A Randomized Clinical Study

Introduction: Gingival recession can cause functional and aesthetic problems, and surgical treatment is often indicated. The use of advanced platelet-rich fibrin (A-PRF) and low-power laser therapy (LLLT) has shown considerable efficacy. Objective: This study evaluated the effectiveness of using A-PRF in combination with LLLT for root coverage in patients with multiple recessions. Methodology: This was a split-mouth, parallel-group, randomized, double-blind study. It was carried out in the dental clinics of the State University of Western Paraná (UNIOESTE), in Cascavel-PR, Brazil. 56 recessions were divided into the Control Group: coronally positioned flap using A-PRF membranes and the LASER Group: coronally positioned flap using A-PRF membranes associated with LLLT. The patients underwent root coverage periodontal surgery associated with A-PRF and on one side of the arch low-power laser was applied postoperatively in 5 sessions: immediately after surgery, 2, 4, 6, and 8 days after the surgical procedure. The patients were followed up for 0, 90, and 180 days to check clinical periodontal parameters, after which the data was subjected to parametric and non-parametric statistical tests, with a 5% significance level considered for all analyses. Results: In both groups, there were improvements in root coverage and keratinized tissue thickness in the periods evaluated (p<0.05), but no statistical difference when comparing the groups (p>0.05). Conclusion: Both the use of A-PRF and A-PRF combined with LLLT provided satisfactory results in covering multiple recessions, although there was no significant superiority between the two treatments, LLLT group clinically showed increased width of keratinized tissue/buccal recession coverage.