Synthesis and cytotoxicity studies of novel <i>N</i>-arylbenzo[<i>h</i>]quinazolin-2-amines
In this paper, we report a short and efficient synthesis of novel <i>N</i>-arylbenzo[<i>h</i>]quinazoline-2-amines. We have prepared a focused library of nineteen representative examples which have been submitted to cytotoxicity assays against a representative panel of eight cancer cell lines and several molecules gave attractive results in this area.
Authors
- Chada Raji Reddy (ORCID: https://orcid.org/0000-0003-1491-7381)
- Nangunoori Sampath Kumar
- B. VEERAIAH
- Kishore Ramineni (ORCID: https://orcid.org/0000-0002-7608-7814)
- Frédéric Justaud
- Dabbugoddu Brahmaiah
- René Grée (ORCID: https://orcid.org/0000-0001-8615-6126)
- Hélène Solhi
- Rémy Le Guével
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Institut des Sciences Chimiques de Rennes (FR)
- Advanced Numerical Research and Analysis Group (IN)
- Structure Fédérative de Recherche en Biologie et Santé de Rennes (FR)
- Indian Institute of Chemical Technology (IN)
- Université de Rennes (FR)
Publication Details
- Journal
- Beilstein Journal of Organic Chemistry
- Published
- 2024-10-14
- DOI
- https://doi.org/10.3762/bjoc.20.218
- Primary Topic
- Quinazolinone synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centre National de la Recherche Scientifique