Hypoxia-Inducible Factor-1α Potentiates Multiterritory Perforator Flap Survival by Augmenting Vascular Endothelial Growth Factor Expression in the Choke II Zone
In summary, HIF-1α enhances the expression of VEGF, promoting angiogenesis in the Choke II zone of the multiterritory perforator flap, thus increasing the survival area.
Authors
- Yunfei Xie (ORCID: https://orcid.org/0000-0002-2758-9236)
- Xiuan Zeng
- Qibing Yang
- Kejing Wang (ORCID: https://orcid.org/0000-0001-5922-3100)
- Tao Guo
- Meng Li (ORCID: https://orcid.org/0000-0003-2123-2444)
- Zhenyang Gao (ORCID: https://orcid.org/0009-0009-3821-6599)
Institutions
- Guiyang Medical University (CN)
- Gansu University of Traditional Chinese Medicine (CN)
- Gansu Provincial Hospital (CN)
Publication Details
- Journal
- Annals of Plastic Surgery
- Published
- 2024-10-14
- DOI
- https://doi.org/10.1097/sap.0000000000004122
- Citations
- 2
- Primary Topic
- Reconstructive Surgery and Microvascular Techniques
- Type
- article
- Field-Weighted Citation Impact
- 1.15