Protective Effect of Aloe-emodin on Cognitive Function in Copper-loaded Rats Based on The Inhibition of Hippocampal Neuron Ferroptosis
These findings suggested that AE mitigates WD copper-loaded rat model hippocampal neuronal damage through the activation of SIRT1-mediated FPT, thereby presenting a valuable candidate Chinese herbal monomer for the clinical treatment of WDCI.
Authors
- Le Tang (ORCID: https://orcid.org/0000-0002-5192-3329)
- Ze Chang
- Wang Xie (ORCID: https://orcid.org/0009-0003-6627-9702)
- Chuanbing Huang (ORCID: https://orcid.org/0000-0002-5832-3094)
- Nan Shao (ORCID: https://orcid.org/0000-0003-4728-5202)
- Juan Zhang (ORCID: https://orcid.org/0000-0003-4673-3448)
- Xiangjun Li (ORCID: https://orcid.org/0000-0001-9919-1238)
- Hong Chen (ORCID: https://orcid.org/0000-0002-9026-9112)
- Daojun Xie (ORCID: https://orcid.org/0000-0003-4237-4855)
- Xiaoyan Zhang (ORCID: https://orcid.org/0009-0002-9650-3800)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Anhui University of Traditional Chinese Medicine (CN)
- Jining Traditional Chinese Medicine Hospital (CN)
- Xiyuan Hospital (CN)
- Shanghai Traditional Chinese Medicine Hospital (CN)
Publication Details
- Journal
- Current Neurovascular Research
- Published
- 2024-10-14
- DOI
- https://doi.org/10.2174/0115672026348862241003042336
- Citations
- 5
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 2.09