Successful Neoadjuvant Chemotherapy and Surgical Removal of a Nonmetastatic Testicular Round Cell Tumor in a Solomon Island Eclectus Parrot (Eclectus roratus solomonensis)
An intracoelomic mass was palpated on an annual exam of a 24-year-old male Solomon Island eclectus parrot (<i>Eclectus roratus solomonensis</i>). The initial diagnostic workup included a complete blood count, plasma biochemistry panel, and coelomic ultrasound. Computed tomography was highly suggestive of a testicular mass. Tamoxifen and the gonadotropin-releasing hormone agonists leuprolide and deslorelin were administered as neoadjunctive endocrine therapies. Biopsy and histologic examination confirmed a testicular mass consistent with a round cell tumor. Four doses of carboplatin 15 mg/kg IV were administered as neoadjunctive chemotherapy, and testicular size decreased by approximately 95%. The remaining gross tumor was removed via orchidectomy with clean but narrow margins. Seven months following surgery, a contrast CT scan did not show any evidence of recurrence of or metastasis from the original mass. This is the first report of successful treatment of a testicular tumor in a psittacine with neoadjuvant chemotherapy and orchidectomy.
Authors
- Brenna Fitzgerald
- Brian L. Speer
- Rachel M. Baden
- Michael M. Garner
- Vanessa Hernández Urraca
Institutions
- University of Colorado Hospital (US)
- OAK Orthopedics (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Journal of Avian Medicine and Surgery
- Published
- 2024-10-07
- DOI
- https://doi.org/10.1647/avianms-d-24-00001
- Citations
- 3
- Primary Topic
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Type
- article
- Field-Weighted Citation Impact
- 1.65