Successful Neoadjuvant Chemotherapy and Surgical Removal of a Nonmetastatic Testicular Round Cell Tumor in a Solomon Island Eclectus Parrot (Eclectus roratus solomonensis)

An intracoelomic mass was palpated on an annual exam of a 24-year-old male Solomon Island eclectus parrot (<i>Eclectus roratus solomonensis</i>). The initial diagnostic workup included a complete blood count, plasma biochemistry panel, and coelomic ultrasound. Computed tomography was highly suggestive of a testicular mass. Tamoxifen and the gonadotropin-releasing hormone agonists leuprolide and deslorelin were administered as neoadjunctive endocrine therapies. Biopsy and histologic examination confirmed a testicular mass consistent with a round cell tumor. Four doses of carboplatin 15 mg/kg IV were administered as neoadjunctive chemotherapy, and testicular size decreased by approximately 95%. The remaining gross tumor was removed via orchidectomy with clean but narrow margins. Seven months following surgery, a contrast CT scan did not show any evidence of recurrence of or metastasis from the original mass. This is the first report of successful treatment of a testicular tumor in a psittacine with neoadjuvant chemotherapy and orchidectomy.

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Publication Details

Journal
Journal of Avian Medicine and Surgery
Published
2024-10-07
DOI
https://doi.org/10.1647/avianms-d-24-00001
Citations
3
Primary Topic
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Type
article
Field-Weighted Citation Impact
1.65
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article

Successful Neoadjuvant Chemotherapy and Surgical Removal of a Nonmetastatic Testicular Round Cell Tumor in a Solomon Island Eclectus Parrot (Eclectus roratus solomonensis)

Brenna Fitzgerald, Brian L. Speer, Rachel M. Baden, Michael M. Garner et al.
3 citations
Journal of Avian Medicine and Surgery
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
1.65
article

Successful Neoadjuvant Chemotherapy and Surgical Removal of a Nonmetastatic Testicular Round Cell Tumor in a Solomon Island Eclectus Parrot (Eclectus roratus solomonensis)

Brenna Fitzgerald, Brian L. Speer, Rachel M. Baden, Michael M. Garner, Vanessa Hernández Urraca
article en
3 citations

Abstract

An intracoelomic mass was palpated on an annual exam of a 24-year-old male Solomon Island eclectus parrot (<i>Eclectus roratus solomonensis</i>). The initial diagnostic workup included a complete blood count, plasma biochemistry panel, and coelomic ultrasound. Computed tomography was highly suggestive of a testicular mass. Tamoxifen and the gonadotropin-releasing hormone agonists leuprolide and deslorelin were administered as neoadjunctive endocrine therapies. Biopsy and histologic examination confirmed a testicular mass consistent with a round cell tumor. Four doses of carboplatin 15 mg/kg IV were administered as neoadjunctive chemotherapy, and testicular size decreased by approximately 95%. The remaining gross tumor was removed via orchidectomy with clean but narrow margins. Seven months following surgery, a contrast CT scan did not show any evidence of recurrence of or metastasis from the original mass. This is the first report of successful treatment of a testicular tumor in a psittacine with neoadjuvant chemotherapy and orchidectomy.

Journal of Avian Medicine and SurgeryVol. 38(3)
University of Colorado Hospital (US), OAK Orthopedics (US), University of Colorado Denver (US)
Openalex Percentile: Top 14%
Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
1.65
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