Curcumin inhibits oxidative stress and autophagy in <scp>C17</scp>.2 neural stem cell through <scp>ERK1</scp>/2 signaling pathways
The findings suggest that curcumin may confer protection against oxidative stress by attenuating autophagy and deactivating the ERK1/2 signaling pathways, which could contribute to therapeutic strategies for Alzheimer's disease.
Authors
- Mengyao Ji (ORCID: https://orcid.org/0000-0003-2469-0045)
- Wang Liao (ORCID: https://orcid.org/0009-0006-4537-3523)
- Jun Liu (ORCID: https://orcid.org/0000-0003-0526-3523)
- Yingren Mai
- Jingyi Tang (ORCID: https://orcid.org/0000-0002-4824-1351)
- Yuting Ruan (ORCID: https://orcid.org/0000-0002-7837-0883)
- Bei Zhang (ORCID: https://orcid.org/0000-0002-4602-5524)
- Haoyu Luo
- Yan Chen (ORCID: https://orcid.org/0000-0002-1397-6358)
- Qun Yu (ORCID: https://orcid.org/0000-0003-3472-9054)
- Yu Dapeng
- Zhiyu Cao
Institutions
- Sun Yat-sen University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- First Affiliated Hospital of Guangdong Pharmaceutical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Aging Medicine
- Published
- 2024-10-01
- DOI
- https://doi.org/10.1002/agm2.12361
- Citations
- 9
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.53
Funders
- Natural Science Foundation of Guangzhou City
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- Traditional Chinese Medicine Bureau of Guangdong Province