The New Era of Total Neoadjuvant FLOT Therapy for Locally Advanced, Resectable Gastric Cancer: A Propensity‐Matched Comparison With Standard Perioperative Therapy
Total neoadjuvant therapy with the FLOT x8 protocol corresponds to higher treatment completion rates, a safety profile similar to standard perioperative therapy, and a twofold increase in complete pathological response. Further research on long-term oncological outcomes is needed to confirm the effectiveness of total neoadjuvant therapy.
Authors
- Derya Salim Uymaz (ORCID: https://orcid.org/0000-0002-2590-5872)
- Emre Özoran (ORCID: https://orcid.org/0000-0002-9371-6811)
- Bengı Gürses (ORCID: https://orcid.org/0000-0002-2482-3445)
- Salih Nafiz Karahan (ORCID: https://orcid.org/0000-0002-3610-7390)
- Duygu Karahacıoğlu (ORCID: https://orcid.org/0000-0003-1365-871X)
- Orhun Çığ Taşkın (ORCID: https://orcid.org/0000-0002-6668-3006)
- Şahin Laçin (ORCID: https://orcid.org/0000-0002-8770-9842)
- Sezer Sağlam (ORCID: https://orcid.org/0000-0001-8954-5792)
- Fatih Selçukbırıcık (ORCID: https://orcid.org/0000-0002-1273-1674)
- Ahmet Rencüzoğulları (ORCID: https://orcid.org/0000-0002-5993-9536)
- İbrahim Halil Özata (ORCID: https://orcid.org/0000-0001-6749-8518)
- Burcu Saka (ORCID: https://orcid.org/0000-0002-2043-2041)
- Dursun Buğra (ORCID: https://orcid.org/0000-0001-7422-5016)
- Emre Balik
Institutions
- Koç University (TR)
- Istanbul Bilim University (TR)
- Amerikan Hastanesi (TR)
Publication Details
- Journal
- Journal of Surgical Oncology
- Published
- 2024-10-13
- DOI
- https://doi.org/10.1002/jso.27934
- Citations
- 9
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 3.77