Capsaicin attenuates the effect of inflammatory cytokines in a HaCaT cell model for basal keratinocytes
These results suggest that activation of TRPV1 by capsaicin can potentiate the increase in <i>CLDN1</i> expression and CLDN1 protein synthesis induced by TNFα in cultured keratinocytes, while reducing the release of IL-8.
Authors
- Veronika Somoza (ORCID: https://orcid.org/0000-0003-2456-9245)
- Barbara Lieder (ORCID: https://orcid.org/0000-0002-0527-8330)
- Dominik Stuhlmann
- Jana Schmidt (ORCID: https://orcid.org/0000-0001-8807-9515)
- Marco Massironi
- Cristina Girardi (ORCID: https://orcid.org/0009-0005-5592-1493)
- Joachim Hans
- Maria Fernanda Cervantes Recalde
- Markus Leo Rechl (ORCID: https://orcid.org/0000-0003-4705-7234)
Institutions
- University of Hohenheim (DE)
- University of Vienna (AT)
- Christian Doppler Laboratory for Thermoelectricity (AT)
- Leibniz-Institute for Food Systems Biology at the Technical University of Munich (DE)
- Symrise (Germany) (DE)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-10-14
- DOI
- https://doi.org/10.3389/fphar.2024.1474898
- Citations
- 3
- Primary Topic
- Barrier Structure and Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.74
Funders
- Symrise