Neonatal overfeeding attenuates microgliosis and hippocampal damage in an infant rat model of pneumococcal meningitis
This study sheds light on the complex interplay between early-life overfeeding, immune response, and neuroprotection in infant rats with PM. The findings demonstrate the neuroprotective impact of early-life overfeeding in the context of PM, linked to the modulation of microglial function.
Authors
- Thomas B. Martins (ORCID: https://orcid.org/0000-0003-3116-0800)
- Larissa Marcely Gomes Cassiano (ORCID: https://orcid.org/0000-0002-6941-0863)
- Roney S. Coimbra (ORCID: https://orcid.org/0000-0002-9204-0573)
- Sarah J. Spencer (ORCID: https://orcid.org/0000-0001-8832-4824)
- Milene Alvarenga Rachid (ORCID: https://orcid.org/0000-0002-3142-6552)
- Ana Karina Holanda Leite Maia (ORCID: https://orcid.org/0000-0003-4094-7218)
- Karina Barbosa de Queiroz
Institutions
- Universidade Federal de Minas Gerais (BR)
- RMIT University (AU)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-14
- DOI
- https://doi.org/10.3389/fimmu.2024.1429157
- Citations
- 1
- Primary Topic
- Bacterial Infections and Vaccines
- Type
- article
- Field-Weighted Citation Impact
- 0.34
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais
- Fundação Oswaldo Cruz