Enhanced joint pain in diabetic patients with knee osteoarthritis is associated with increased synovitis, synovial immune cell infiltration, and erythrocyte extravasation
The study suggests that increased OA progression and pain severity in patients with DM result from more pronounced synovitis and synovial vascular leakage and increased infiltration of macrophages and mast cells.
Authors
- Gunther O. Hofmann (ORCID: https://orcid.org/0000-0003-2261-214X)
- Ivan Marintschev (ORCID: https://orcid.org/0000-0002-9470-277X)
- Hans‐Georg Schaible (ORCID: https://orcid.org/0000-0002-4708-2221)
- Annett Eitner (ORCID: https://orcid.org/0000-0002-0590-3001)
- Veronika Rutte
Institutions
- Jena University Hospital (DE)
- Friedrich Schiller University Jena (DE)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2024-10-14
- DOI
- https://doi.org/10.3389/fendo.2024.1477384
- Citations
- 7
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.29